How does STRmix™ NGS work?

STRmix™ NGS combines sophisticated biological modelling and standard mathematical processes to interpret a wide range of complex NGS STR DNA profiles. 

Using well-established statistical methods, the software builds millions of conceptual DNA profiles. It grades them against the evidential sample, finding the combinations that best explain the profile.

 

Validation

The STRmix™ NGS workflow and user experience is grounded on the capillary electrophoresis-based STRmix™ technology, which has been extensively validated and used for casework interpretation at ESR and multiple Australian, US, Canadian, European, Asian, and UK laboratories (first implemented in August 2012).