DNA analysis is a process of identifying alleles. The alleles appear as peaks in an electropherogram (EPG) and are identified from their locations within the EPG. The locations are determined using internal size standards and ‘ladders’.
Contains the size-standard and ladder data for commonly-available testing kits. Additional kits and size standards can easily be added by importing panel, bin, and size standard information, or by manual entry.
Based on an adaptation of the methods implemented in OSIRIS, FaSTR™ DNA applies a set of fully configurable rules to identify and label alleles and reject artefacts within the EPGs of test samples.
EPGs are produced by genetic analysers in the form of .fsa or .hid data files. These files are the input to FaSTR™ DNA. FaSTR™ DNA analyses EPG data in steps by:
 R.M. Goor, L. Forman Neall, D. Hoffman, S.T. Sherry, Mathematical approach to analysis of multiplex DNA profiles, Bull Math Biol 73(8) (2011) 1909-1931
FaSTR™ DNA displays the results of its analysis (the ‘DNA profile’), as a labelled EPG and as a table of loci and peak designations. With FaSTR™ DNA you can:
The analysis settings can be general or specific to each STR kit type and locus. FaSTR™ DNA contains easily customisable default kits and methods. You can also create (and save) customised sets of parameters appropriate to different types of DNA samples (e.g. single-source samples and crime-scene samples).